Improving cognition using nutritional supplementation(60-75yrs old)

Trial Name

The effects of 12 months administration of Bacopa, Pycnogenol and an antioxidant/micronutrient combination formula on cognitive function in a healthy older population.

Background Information

The Centre for Human Psychopharmacology at Swinburne University of Technology is currently investigating the effectiveness of Bacopa monniera, Pycnogenol and a combination formula in improving cognitive function and other health measures in healthy older adults.

Bacopa has been used in Indian medicine for over 3000 years as a memory and intellect enhancer. Previous research has found Bacopa to have anti-inflammatory and antioxidant properties, which may play an important role in maintaining healthy brain function, and that it has beneficial cognitive effects for example in memory.

Pycnogenol is an extract of the French maritime pine tree which is a powerful blend of antioxidants helping to protect the brain from oxygen free radicals that occur during normal metabolism and that increases in aging. It has shown to slow age-related decline in animal models and pilot data from our laboratory has demonstrated Pycnogenol to improve working memory and reduce markers of oxidative stress.

The combination formula includes a strategic blend of antioxidants and micronutrients (Folic acid 400 mcg, Vitamin B12 6 mcg, Vitamin E 30 IU, CoQ10 50 mg, Lipoic acid 400 mg, Phosphatidylserine 200 mg, Acetyl-L-carnitine 500 mg) aimed at improving cognitive performance. This formula may help protect the brain and cardiovascular system from increases in oxidative stress associated with normal metabolism and ageing.

We are seeking healthy, older volunteers to help us investigate the effects of these supplements on cognition, cardiovascular function and other markers of health.


Victoria - Hawthorn

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